Close Menu
LiveHealthNews
    What's Hot
    Health

    The Adriana Smith Case Was an Ethical Disaster

    Garden

    Laying Cover Crops in 7 Steps

    Health

    What Can Be Mistaken for Trigeminal Neuralgia? Find Here

    Important Pages:
    • Home
    • About Us
    • Contact us
    • Privacy Policy
    • Terms & Conditions
    Facebook X (Twitter) Instagram Pinterest
    • Home
    • About Us
    • Contact us
    • Privacy Policy
    • Terms & Conditions
    Facebook X (Twitter) Instagram Pinterest
    LiveHealthNews
    • Health

      How to Build a Financial Safety Net for Your Health

      The NIH Has Two Months Left to Spend Billions

      What’s So Bad About Nicotine?

      The Simple Sleep Hack That Can Be Lifechanging

      Vinay Prasad Was Too MAHA for the Trump Administration

    • Lifestyle

      7 Best British Comedies Of All Time, Ranked

      Using Psychology To Make Someone Fall (And Stay) In Love With You

      Top 10 Worst Fictional Girlfriends

      This Is How You Love Someone Who Constantly Overthinks

      5 Best Mouth Tapes for Sleeping of 2025

    • Wellness

      Nordstrom Anniversary Sale 2023 Picks!

      Why and How To Develop a Daily Writing Routine

      How Long Should You Workout a Day?

      I Tried Journaling in the Morning for 30 Days

      What Is the Best Time To Walk During the Day?

    • Beauty

      Homemade Herbal Lip Balm

      Why an Essence Toner Deserves a Spot in Your Routine

      Exactly How Your Skin Changes in Your 40s, 50s, and 60s

      Is It a Terrible Idea to Get Botox at a Medi-spa?

      Do Biotin Supplements Actually Do Anything for Hair Loss?

    • Fitness

      9 Best Joggers for Women to Wear Every Day in 2025

      Lagree vs. Pilates: Which Method Gives You a Better Workout?

      Building a Mental Health-Focused Home Gym

      8 Best Hiking Sandals of 2025, According to Experts

      The Best Golf Clothes for Women in 2025: Look Like a Pro

    • Weight Loss

      Tamicka lost 39 pounds – Black Weight Loss Success

      8.1 Friday Faves – The Fitnessista

      188: Heal Your Body from the Inside Out with Dr. Jonathan Carp of Miracle Noodle

      Easy solo parenting dinner ideas

      187: Food Freedom & Clarity with Carnivore Coach Mark Ennis

    • Garden

      How to Know if Your Carrots Are Ready to Harvest

      How to Grow and Care for Graptosedum Succulents

      The Ultimate Guide to Burgundy and Wine-Colored Perennial Flowers

      17 of the Best Tillandsia Air Plant Varieties

      How to Plant, Grow, and Care for Champagne Grapes

    LiveHealthNews
    Home » What Happens When You Stop Taking Mounjaro or Ozempic?
    Weight Loss

    What Happens When You Stop Taking Mounjaro or Ozempic?

    Share Facebook Twitter Pinterest WhatsApp
    What Happens When You Stop Taking Mounjaro or Ozempic?
    Share
    Facebook Twitter Pinterest WhatsApp

    For those who’ve been trying to find new methods to advance your weight reduction efforts, you’ve most likely heard about incretin mimetic medication like Mounjaro, Ozempic, Rybelsus, Wegovy, and Zepbound. Many individuals have reported dramatic weight reduction by taking a lot of these drugs.

    However what occurs while you cease taking incretin mimetics for weight reduction? Do you achieve weight again after quitting, or do you must take them without end to keep up your outcomes?

    Brief reply: Once you cease taking incretin mimetics, you’ll probably regain many of the weight you misplaced.

    That may be discouraging when you think about the downsides of long-term use. For starters, there’s the price — each Mounjaro and Ozempic have an inventory value of about $1,000 for a month’s provide. Out-of-pocket prices will differ primarily based in your insurance coverage plan, however they will add up shortly, particularly if you must issue them into your month-to-month funds without end.

    These drugs are additionally comparatively new to the scene, which suggests their long-term results is probably not absolutely understood. It’s essential to weigh all of the potential dangers and rewards earlier than deciding whether or not incretin mimetics are best for you. And, in fact, you must all the time speak to your physician earlier than beginning (or stopping!) any treatment.

    For those who’re contemplating incretin mimetics or their kin for weight reduction, right here’s what you should know.

    How Do Mounjaro and Ozempic Work?

    Woman Injects Mounjaro to Belly | what happens when you stop taking Mounjaro

    Mounjaro, Zepbound, Ozempic, Rybelsus, and Wegovy work by mimicking metabolic hormones known as incretins. Therefore, these medication are known as incretin mimetics.

    This hormonal mimicry enhances the physique’s capacity to keep up wholesome blood sugar ranges. It additionally helps scale back urge for food and meals consumption by making you are feeling full sooner and for longer after consuming. Because of this, many individuals expertise weight reduction as a secondary impact.

    Whereas these medication all work in comparatively comparable methods, there are a number of key variations relating to their mechanisms of motion and supposed use.

    Semaglutide mechanism of motion

    Ozempic, Rybelsus, Wegovy are manufactured by Novo Nordisk and comprise the identical lively ingredient, semaglutide. By mimicking a hormone known as glucagon-like peptide-1 (GLP-1), semaglutide helps to advertise insulin manufacturing, gradual digestion, and suppress urge for food.

    Ozempic (injectable) and Rybelsus (tablet type) are each FDA-approved as first-line remedies for kind 2 diabetes. Nonetheless, docs will generally prescribe these drugs off-label — i.e., not as directed — for weight reduction.

    Wegovy, alternatively, is an FDA-approved, injectable model of semaglutide formulated particularly for weight administration. It’s supposed for adults with weight problems or chubby adults with a minimum of one weight-related well being situation.

    Tirzepatide mechanism of motion

    The lively ingredient in each Mounjaro and Zepbound is tirzepatide. Like semaglutide, tirzepatide mimics the GLP-1 hormone and will increase insulin sensitivity. However tirzepatide’s mechanism of motion additionally mimics the gastric inhibitory peptide hormone (GIP), which helps to advertise insulin secretion and regulate urge for food and satiety.

    “There have been research that present that tirzepatide ends in extra weight reduction than semaglutide,” says Mir Ali, MD, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Middle at Orange Coast Medical Middle in Fountain Valley, CA. “This has been attributed to affecting two receptors reasonably than one.”

    Mounjaro and Zepbound, that are each administered by way of once-weekly injections, are manufactured by Eli Lilly. Mounjaro is FDA-approved as a diabetes treatment, whereas Zepbound is accredited for weight administration in adults with weight problems, or chubby adults with a minimum of one weight-related well being situation. (Sound acquainted?)

    Like Ozempic and Rybelsus, Mounjaro could also be prescribed off-label for weight reduction.

    What Occurs When You Cease Taking GLP-1 Medication for Weight Loss?

    man eating food with friends | What Happens When You Stop Taking Mounjaro?

    Incretin mimetics might help with weight administration when you’re taking them. However while you cease taking these medication, your metabolic perform will revert again to its pre-medication state, and the quantity on the dimensions will probably comply with go well with.

    Listed below are a number of frequent unwanted effects of stopping Mounjaro, Ozempic, and the like:

    1. Your urge for food will make a comeback

    “[Incretin mimetics’] main impact for weight reduction is to suppress the urge for food and gradual the emptying of the abdomen,” Ali says. “As soon as the treatment is stopped, the urge for food returns to its earlier state and the abdomen resumes emptying on the regular price. These processes can result in an individual desirous to eat extra.”

    2. You’ll probably regain a lot of the burden you misplaced

    As soon as your urge for food is again in full swing, you’ll must maintain a detailed eye in your calorie consumption. “If the affected person isn’t cautious, they will begin regaining weight,” Ali says.

    One medical trial discovered that, a yr after stopping incretin mimetics, individuals had regained a median of two-thirds of the burden they’d initially misplaced. Their cardiometabolic enhancements went again to baseline, too.

    3. Your blood sugar could rise

    Once you cease taking incretin mimetics, Ali says, insulin secretion returns to its earlier state and it’s possible you’ll discover a rise in your blood glucose ranges. In a latest peer-reviewed research, researchers divided individuals into 4 teams. Three teams took tirzepatide in various doses, whereas the fourth group was given the kind 2 diabetes drug dulaglutide.

    One yr later, all three tirzepatide teams had larger enhancements in blood glucose ranges than the dulaglutide group. Nonetheless, two months after stopping therapy, all 4 teams had re-elevated blood glucose ranges — and the tirzepatide teams had been already experiencing rebound weight achieve.

    The research authors concluded that their findings “recommend a necessity for steady prescription or cautious follow-up when stopping.”

    Can You Simply Cease Taking Mounjaro and Ozempic?

    Given the extent to which long-term medication like semaglutide and tirzepatide have an effect on the physique, quitting chilly turkey isn’t suggested with out the steerage of a doctor. That mentioned, there isn’t a compelling proof that discontinuing their use will trigger severe withdrawal signs.

    There is a rising physique of analysis, nonetheless, suggesting that many individuals expertise a “speedy rebound” in blood glucose ranges and weight achieve after stopping incretin mimetics. These results “are usually not thought of withdrawal signs, however the return of the affected person’s prior physiology,” Ali says.

    Preserving weight reduction after quitting incretin mimetics

    When you’ve hit your weight reduction targets, it could be attainable to cease taking semaglutide and tirzepatide with out regaining a lot weight. However you’ll have to be ready to make use of the next life-style methods:

    “If a affected person is ready to make important, long-term dietary and life-style adjustments, then they’ve a greater probability of maintaining the burden off when the drugs are stopped,” Ali says.

    As all the time, you will need to keep in mind you must all the time seek the advice of a healthcare supplier earlier than stopping and restarting Mounjaro, Ozempic, or another such treatment.

    Ought to You Contemplate Taking Weight Loss Medication?

    Woman Holds Mounjaro Injector | what happens when you stop taking Mounjaro

    Incretin mimetics could also be getting a number of hype, nevertheless it’s essential to notice that they’re supposed to be long-term remedies for persistent well being points — not only a fast technique to lose a number of cussed kilos.

    “These drugs are designed for sufferers categorized as overweight with a physique mass index over 30, or over 27 with different co-morbid situations,” Ali says.

    Even for many who meet the medical standards, a weight reduction drug isn’t any substitute for a balanced eating regimen and common train. Consuming nutrient-dense meals continues to be one of the best ways to get the nutritional vitamins, minerals, fiber, and antioxidants you want. And a weight reduction treatment can’t stand in for train relating to bettering power, cardio capability, coronary heart well being, bone well being, and extra.

    How Lengthy Do GLP-1 Medication Keep in Your System?

    In response to the Meals and Drug Administration, the half-life of tirzepatide is about 5 days. Which means while you cease taking these medication, it could take round a month for the drug to be utterly gone out of your physique.

    The half-life of semaglutide is round seven days, so while you cease taking these medication, it could keep in your system for about 5 weeks after the final dose.

    Nonetheless, to keep up their effectiveness, semaglutides and tirzepatides are prescribed for weekly use, they usually’re supposed for use indefinitely. “Weight problems is being regarded as a persistent illness, resembling diabetes or hypertension, so sufferers could have to be on these drugs long-term,” Ali says.

    What's Your Reaction?

    • OMGOMG
      0
      OMG
    • LOVELOVE
      0
      LOVE
    • CuteCute
      0
      Cute

    Share. Facebook Twitter Pinterest WhatsApp
    Previous ArticleThis Upcoming Film Is Poised To Be 2025’s Most Powerful Romance Drama
    Next Article RFK Jr. and MAHA’s Trivialization of Measles

    Related Posts

    Weight Loss

    Tamicka lost 39 pounds – Black Weight Loss Success

    Weight Loss

    8.1 Friday Faves – The Fitnessista

    Weight Loss

    188: Heal Your Body from the Inside Out with Dr. Jonathan Carp of Miracle Noodle

    Weight Loss

    Easy solo parenting dinner ideas

    Weight Loss

    187: Food Freedom & Clarity with Carnivore Coach Mark Ennis

    Weight Loss

    Autumn lost 16 pounds – Black Weight Loss Success

    Weight Loss

    My Healthy Sleep Stack: What I Use for Deep, Restorative Rest

    Weight Loss

    7.18 Friday Faves – The Fitnessista

    Add A Comment
    Leave A Reply Cancel Reply

    Good Deal
    Don't Miss
    Fitness

    A 12-Minute Kettlebell Arms Workout to Fire Up Your Biceps and Triceps

    Generally, it’s good to take your time within the health club. Different occasions you don’t…

    37 of the Best Cold Hardy Clematis Varieties

    Mom Feet Is a Baffling Pregnancy Surprise

    21 of the Best Cold-Hardy Shrubs for Winter Interest

    Three Tips for Better Sleep

    May You Like This

    LiveHealthNews is a Professional Health & Lifestyle Blog. Here we will provide you with only exciting content that you will enjoy and find useful. We’re working to turn our passion into a successful website. We hope you enjoy our Content as much as we enjoy offering them to you.

    Facebook X (Twitter) Instagram Pinterest
    Categories
    • Beauty (230)
    • Fitness (761)
    • Garden (1,378)
    • Health (1,165)
    • Lifestyle (1,032)
    • Weight Loss (914)
    • Wellness (150)
    Most Popular
    Lifestyle

    Every Diddy Documentary To Stream As The Legal Proceedings Unfold

    Wellness

    Active Recovery Exercises: What to Do on Your Rest Day

    Lifestyle

    ‘Date With Me’ TikTok Trend: Therapists Are Wary

    © 2025 LiveHealthNews.
    • Home
    • About Us
    • Contact us
    • Privacy Policy
    • Terms & Conditions

    Type above and press Enter to search. Press Esc to cancel.

    Ad Blocker Enabled!
    Ad Blocker Enabled!
    Our website is made possible by displaying online advertisements to our visitors. Please support us by disabling your Ad Blocker.